Archive for 2009/08


Roflumilast Treatment Shows Promise For Some Patients With COPD

Roflumilast, an oral, once a day anti-inflammatory agent, improves lung function and reduces exacerbations in patients with chronic obstructive pulmonary disease (COPD) who have chronic respiratory symptoms and are at greater risk of exacerbations. The effect persists even when roflumilast is added to conventional treatment with inhaled long-acting bronchodilators. Thus, roflumilast therapy has the potential to become an important treatment for these patients.
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08/31/2009 | Respiratory & Asthma - COPD | Trackback | Comments Off

COPD Patients Should Begin Treatment At An Earlier Stage

While the effectiveness of drug therapy for COPD patients at advanced stages of disease has been proven, little evidence exists regarding starting treatment at earlier stages. The findings of the UPLIFT study, published in an Article Online First to coincide with this week's COPD special issue of The Lancet, show that treatment with inhaled tiotropium at an earlier stage of COPD reduces decline of lung function-and thus treatment should begin at this earlier stage.
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08/31/2009 | Respiratory & Asthma - COPD | Trackback | Comments Off

Use Of Inhaled Corticosteroid Budesonide Does Not Increase Risk Of Pneumonia In Lung Disease Patients

Contrary to other research findings, patients using the inhaled corticosteroid budesonide to treat Chronic Obstructive Pulmonary Disease (COPD) are not at increased risk of pneumonia, and the drug is safe to use in these patients, concludes an Article in this week's COPD special issue of The Lancet. Inhaled corticosteroids are prescribed with and without beta-antagonists to relieve the symptoms and improve the quality of life for patients with COPD.
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08/30/2009 | Respiratory & Asthma - Respiratory / Asthma | Trackback | Comments Off

Predictive Tool May Help Determine Treatment Of COPD Patients

A new score, the ADO index, for predicting a patient's risk of dying from chronic obstructive pulmonary disease (COPD) performs better than the current test and is much more applicable in clinical practice. It could help doctors target suitable treatment options to individual patients, finds an Article to be published in this week's COPD special edition of The Lancet.
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08/30/2009 | Respiratory & Asthma - COPD | Trackback | Comments Off

Four Studies Published In The Lancet Show Roflumilast (Daxas(R)), A New Oral Approach To COPD, Improves Lung Function And Reduces Exacerbations

Forest Laboratories, Inc. (NYSE: FRX), an international pharmaceutical manufacturer and marketer and Nycomed, a privately owned pharmaceutical company, announced that results of four phase III trials have been published in the prestigious peer-reviewed medical journal The Lancet showing that roflumilast, a phosphodiesterase 4 (PDE4) inhibitor, improved lung function and reduced exacerbations in patients with moderate to severe COPD.
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08/30/2009 | Respiratory & Asthma - COPD | Trackback | Comments Off

Air Pollution In Tunnels Concentrated By Up To 1000 Times

A toxic cocktail of ultrafine particles is lurking inside road tunnels in concentration levels so high they have the potential to harm drivers and passengers, a new study has found. The study, which has been published in Atmospheric Environment, measured ultrafine particle concentration levels outside a vehicle travelling through the M5 East tunnel in Sydney.
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08/28/2009 | Respiratory & Asthma - Water - Air Quality / Agriculture | Trackback | Comments Off

Warnex Launches Test For Influenza A H1N1 Virus Mutation Associated With Resistance To Tamiflu(R)

Warnex Inc. (TSX:WNX) announced today that its Medical Laboratories division has launched a test for the detection of a mutation of the pandemic influenza A H1N1 virus, which is associated with resistance to Tamiflu®, a drug used for the treatment and prevention of the flu. The test specifically detects the H275Y mutation of the neuraminidase gene, which has been shown to cause resistance to Tamiflu.
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08/28/2009 | Respiratory & Asthma - Swine Flu | Trackback | Comments Off

Back To School With Asthma

Buying new school supplies is a late summer ritual for many parents. But for parents of children with asthma, getting ready for school also means getting prepared for the "September spike" - the annual peak in asthma flare-ups that sends hundreds of school children and their family members to emergency rooms in the weeks after school begins.
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08/28/2009 | Respiratory & Asthma - Respiratory / Asthma | Trackback | Comments Off

New Tech Cuts Industrial Odors, Pollutants

A North Carolina State University researcher has devised a new technology that really does not stink. In fact, it could be the key to eliminating foul odors and air pollutants emitted by industrial chicken rendering facilities and - ultimately - large-scale swine feedlots. Dr. Praveen Kolar, assistant professor of biological and agricultural engineering at NC State, has developed an inexpensive treatment process that significantly mitigates odors from poultry rendering operations.
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08/27/2009 | Respiratory & Asthma - Water - Air Quality / Agriculture | Trackback | Comments Off

Researchers Find Common Respiratory Virus Hijacks Lung Cells To Stay Alive

Approximately one-half of all infants are infected with the respiratory syncytial virus (RSV) during the first year of life, and almost all children have been infected at least once by the time they reach their second birthday. Researchers at West Virginia University have discovered what makes RSV such a severe and persistent illness. Senior author Giovanni Piedimonte, M.D.
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08/27/2009 | Respiratory & Asthma - Respiratory / Asthma | Trackback | Comments Off

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