Archive for 2006/10


Home Nebulizer Misuse May Contribute To Death

A new study suggests that the misuse of home nebulizers may have been a contributing cause of patient deaths in Michigan. All asthma-related deaths in Michigan, between 2002 to 2004, in patients 2- to 34-years-old, were identified. In total, 86 deaths occurred, 38 of which were children. Researchers from Michigan State University collected medical records for the year prior to death, and interviews with next of kin were obtained and examined by an expert panel. [click link for full article]
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Large Community Spirometry Screening Proves Successful

Large scale, community spiromety screening for chronic obstructive pulmonary disease (COPD), can be successfully performed in non-traditional settings, according to a new study. The research, presented at CHEST 2006, the 72nd annual international scientific assembly of the American College of Chest Physicians (ACCP), also demonstrates that community spirometry screenings can identify a large proportion of subjects with significant impairment. [click link for full article]
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Asthma May Be Overdiagnosed In Obese Patients

A new study reveals that, despite lack of evidence, obese patients are often diagnosed with asthma. Researchers at Newark Beth Israel Medical Center in New Jersey studied 20 patients, all of whom had a diagnosis of asthma, but none of whom exhibited any spirometric evidence of airway obstruction. The body mass index (BMI) was calculated, and bronchoprovocations tests were performed. In all, 90 percent of patients had an above-normal BMI. [click link for full article]
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Pulmonary Hypertension Discrimination: Mortality Highest Among African American Women

African-American women have the highest mortality rate for idiopathic pulmonary arterial hypertension (IPAH), according to new research. The study, presented at CHEST 2006, the 72nd annual international scientific assembly of the American College of Chest Physicians (ACCP), revealed that racial disparities exist in pulmonary hypertension mortality and morbidity, with African-American women exhibiting the highest mortality rate when compared with all other groups. [click link for full article]
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Cell Wall Of Pneumonia Bacteria Can Cause Brain And Heart Damage

Investigators at St. Jude Children's Research Hospital have discovered in mouse models how cell walls from certain pneumonia-causing bacteria can cause fatal heart damage; researchers have also shown how antibiotic therapy can contribute to this damage by increasing the number of cell wall pieces shed by dying bacteria. The team also demonstrated in a mouse model how to prevent this from happening. [click link for full article]
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Pediatric Rapid Response Team At Yale Reduces Cardiorespiratory Arrests

Yale School of Medicine's Department of Pediatrics and the Pediatric Intensive Care Unit at Yale-New Haven Hospital have been recognized by the Institute for Healthcare Improvement for implementing a rapid response team that aims to reduce the numbers of cardiorespiratory arrests in pediatric patients.Cardiorespiratory arrests, in which respiration and circulation stops, is usually associated with adults, but also affects about seven percent of pediatric patients. [click link for full article]
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Large Community Spirometry Screening For COPD Proves Successful

Large scale, community spiromety screening for chronic obstructive pulmonary disease (COPD), can be successfully performed in non-traditional settings, according to a new study. The research, presented at CHEST 2006, the 72nd annual international scientific assembly of the American College of Chest Physicians (ACCP), also demonstrates that community spirometry screenings can identify a large proportion of subjects with significant impairment. [click link for full article]
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Anxiety Disorders And Physical Conditions Linked

Anxiety disorders appear to be independently associated with several physical conditions, including thyroid disease, respiratory disease, arthritis and migraine headaches, according to a report in the October 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. This co-occurrence of disorders may significantly increase the risk of disability and negatively affect quality of life. [click link for full article]
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Tanox Initiates Phase 1 Clinical Trial Evaluating TNX-650 For Treatment Of Asthma

Tanox, Inc. (Nasdaq: TNOX) has begun dosing a Phase 1 clinical trial of TNX-650, a humanized monoclonal antibody being evaluated as a potential treatment for moderate-to-severe asthma. The trial is a randomized, double-blind, placebo-controlled, dose- escalation study of the safety, tolerability and pharmacokinetics of single doses of TNX-650 in healthy volunteers. [click link for full article]
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“Molecular Inch-Worm” Structure Of Walking-Pneumonia Bacterium, Unravelled by UGA Scientists

Researchers at the University of Georgia, using glow-in-the-dark proteins and microcinematography, have helped unravel the development and function of a complex organelle in the bacterium that causes "walking pneumonia."The researchers have described in new, precise detail the unique cell extension that forms on one end of the bacterium Mycoplasma pneumoniae. [click link for full article]
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