Archive for the 'Pediatrics / Children's Health' Category


Antenatal Infection Compromises Post-Natal Growth And Lung Development In The Premature Baby

Christèle Gras-Le Guen (Hôpital Mère Enfant CHU Nantes, France) and colleagues report an experimental work in the rabbit in order to confirm an association, previously reported in humans, between antenatal infection and post-natal bronchopulmonary dysplasia (BPD), the most serious respiratory disease in premature babies. This study has been conducted in an experimental model of Escherichia coli antenatal infection in the rabbit.
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Gene Mutation May Cause Immature Lungs In Newborns

Scientists have identified a gene critical to lung maturation in newborns and the production of surfactant, which lines lung tissues and prevents the lungs from collapsing. In a study posted online by the Proceedings of the National Academy of Sciences (PNAS), investigators at Cincinnati Children's Hospital Medical Center deleted the Foxm1 gene in embryonic mice.
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Fall Babies Born To Wheeze? New Evidence Links Birth Season To Asthma Development

It is said that timing is everything, and that certainly appears to be true for autumn infants. Children who are born four months before the height of cold and flu season have a greater risk of developing childhood asthma than children born at any other time of year, according to new research.
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Smiths Medical Announces New Partnership With Great Ormond Street Hospital And University College London

Smiths Medical announces a new five-year research partnership with Great Ormond Street Hospital (GOSH), the Institute of Child Health (ICH) and University College London (UCL). The partnership will provide sponsorship for the Smiths Medical Professor of Anaesthesia and Critical Care at UCL.
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Breastfed Kids Breathe More Easily

Breastfeeding for at least four months helps children breathe more easily and may curb their susceptibility to asthma, reveals research published ahead of print in the journal Thorax. The findings are based on almost 1500 British children born on the Isle of Wight between 1989 and 1990 (Isle of Wight Birth Cohort), whose respiratory health was tracked at the ages of 1, 2, 4 and 10. Extensive information was gathered during their check-ups.
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Respiratory Syncytial Virus Is Like A Cold In Most Children, But A Serious Illness For Some

Because what seems to be a common cold can land some babies in the hospital, RSV is a scary illness for parents of infants and toddlers. RSV (respiratory syncytial virus) is so common that half of all children have had it by age 1, and virtually all have had it by age 2, said Dr. Shannon Hoime, pediatrician with McGreevy Clinic Avera in Sioux Falls.
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CHEST 2008: New Research In Pediatric Chest Medicine

#6967 ASTHMA IN CHILDREN CHANGES WITH THE SEASONS Health-care utilization for children with asthma changes with the seasons, peaking in the fall. Using data from the United Healthcare database, researchers from the University of North Carolina reviewed health-care utilization patterns and asthma medication usage in children aged 2 to 5 years and 6 to 12 years from 2002 to 2004.
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Phase 3 Data Indicate Investigational 13-valent Vaccine May Broaden Protection Against Pneumoccocal Disease In Children Younger Than Two

Data from a pivotal trial and three other Phase 3 studies presented today indicate that Wyeth's (NYSE: WYE) investigational 13-valent pneumococcal conjugate vaccine (PCV13) may offer broader protection against pneumococcal disease (PD) in infants and young children compared to Prevnar(R), Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein).
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Data Presented By MedImmune At AAP National Conference & Exhibition Demonstrating Burden Of RSV Disease

MedImmune has announced that it will present four abstracts at the American Academy of Pediatrics (AAP) 2008 National Conference & Exhibition that add to the company's growing body of research into the prevention of respiratory syncytial virus (RSV), a leading cause of viral respiratory infection among preterm infants. "As we gain data that further demonstrate the burden of RSV disease on preterm babies, the benefits of preventive care become more evident," said Jessie R.
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Risk Factors Outside Of AAP Guidelines Identify More Preemies Needing RSV Prophylaxis

New data have emerged regarding three risk factors which may help pediatricians better identify which preterm infants are at high risk of severe respiratory syncytial virus (RSV) disease and may thus benefit from palivizumab (Synagis®) prophylaxis, investigators reported at the American Academy of Pediatrics (AAP) 2008 National Conference and Exhibition. The risk factors include cigarette smoking, crowded living conditions, and young chronologic age.
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