Archive for the 'Cystic Fibrosis' Category


Early Cystic Fibrosis Detected Using Bronchoalveolar Lavage And Lung Clearance Index

According to a new Australian study published online before he print publication in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine, the lung clearance index (LCI) is a sensitive, non-invasive marker of early lung disease in young children with cystic fibrosis (CF)…


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Cystic Fibrosis - Inhaling Mannitol Plus Standard therapy Improves Lung Function

A new study found that the combination of inhaled dry powder mannitol with standard therapy for cystic fibrosis resulted in maintained improvement in lung function for 12 months. In addition to being effective and safe, the easy administration of the treatment might help enhance adherence with treatment in individuals suffering with the condition…


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Inhaled Dry Powder Mannitol Improves Lung Function In CF

Adding inhaled dry powder mannitol to standard therapy for cystic fibrosis produced sustained improvement in lung function for up to 52 weeks, according to a new study. Along with the treatment’s efficacy and good safety profile, the convenience and ease of administration of mannitol treatment may improve adherence with therapy in these patients…


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New Invasive Diagnostic Procedure Seems To Be Of No Advantage Over Current Standard Procedure In Infants With Cystic Fibrosis

A comparative study published in July 13 issue of JAMA noticed, treatment based on a new invasive diagnostic procedure for treating cystic fibrosis in infants that involves obtaining and culturing fluid samples from the lungs, when compared with standard diagnostic procedure, did not have a lower prevalence of lung-damaging infection or structural lung injury at 5 years of age…


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Lamellar Biomedical Secures Its First Orphan Drug Licence

Glasgow biopharmaceutical firm, Lamellar Biomedical Ltd, launched four years ago to develop a new class of therapies for the prevention, treatment and control of severe respiratory disease, today announced that their lead clinical candidate LMS-611 for the treatment of patients with cystic fibrosis has received Orphan Drug Designation from the European Commission…


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Insmed’s ARIKACE® Demonstrates Sustained Benefit Through Six Cycles Of Treatment For Cystic Fibrosis Patients With Pseudomonas Lung Infections

Insmed Incorporated (Nasdaq CM: INSM), a biopharmaceutical company, announced positive data through six treatment cycles (72 weeks total duration) of its Phase 2 clinical trial program for ARIKACE® (liposomal amikacin for inhalation) in cystic fibrosis (CF) patients with Pseudomonas lung infections…


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Researchers Identify Genes Linked To Worsening Of Cystic Fibrosis

A team of international researchers, including Case Western Reserve University School of Medicine, have discovered regions of the genome that affect the severity of the genetic disease cystic fibrosis (CF), the most common lethal genetic disease affecting children in North America…


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Simple Exercise Improves Lung Function In Children With CF

A small Johns Hopkins Children’s Center study of children and teens with cystic fibrosis (CF) shows that simple exercise, individually tailored to each patient’s preference and lifestyle, can help improve lung function and overall fitness…


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TIGER-1 Denufosol Phase 3 Trial For Cystic Fibrosis Published In The American Journal Of Respiratory And Critical Care Medicine

Inspire Pharmaceuticals, Inc. (NASDAQ: ISPH) announced that the results from its first Phase 3 clinical trial with denufosol tetrasodium for cystic fibrosis (CF), TIGER-1, have been published in the peer-reviewed publication, American Journal of Respiratory and Critical Care Medicine (AJRCCM)…


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ARIKACE™ Demonstrates Sustained Benefit In Multiple Studies And Over Multiple Cycles Of Treatment Of Pseudomonas Lung Infections

Transave, Inc., reported positive clinical trial results on its lead investigational drug, ARIKACE™ (liposomal amikacin for inhalation), an antibiotic that is entering Phase III development for the treatment of chronic lung infections...
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